Zoledronic acid for neonatal subcutaneous fat necrosis
نویسندگان
چکیده
Subcutaneous fat necrosis (SFN) in infants producing severe hypercalcemia is a life-threatening emergency. Pathophysiology may include enhanced gastrointestinal calcium absorption and bone resorption. We treated an infant with SFN and serum calcium of 15 mg/dL with prednisolone and low-dose zoledronic acid. Serum calcium promptly normalized without rebound hypocalcemia, and redosing of zoledronic acid was not necessary.
منابع مشابه
Hypercalcaemia Associated with Neonatal Subcutaneous Fat Necrosis.
Localized neonatal subcutaneous fat necrosis has been well recognized since the description of Fabyan (1907). Since then many case reports have been published: thus Masi and Brancolini (1956) collected 179 reported cases. Calcium deposition in affected tissues was described by Harrison and McNee (1926) and a raised serum calcium was reported in one of their cases. The association of this condit...
متن کاملHypercalcaemia Associated with Neonatal Subcutaneous Fat Necrosis By
Localized neonatal subcutaneous fat necrosis has been well recognized since the description of Fabyan (1907). Since then many case reports have been published: thus Masi and Brancolini (1956) collected 179 reported cases. Calcium deposition in affected tissues was described by Harrison and McNee (1926) and a raised serum calcium was reported in one of their cases. The association of this condit...
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